Cymbalta® Withdrawal Symptoms

Cymbalta Withdrawal Symptoms

We are no longer accepting new Cymbalta withdrawal cases.

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What Are Cymbalta Withdrawal Symptoms?

According to the current drug label for Cymbalta, the following symptoms occurred in patients who discontinued Cymbalta:

  • Dizziness
  • Nausea
  • Headache
  • Paresthesia (prickling or electric shock sensations, commonly called brain zaps)
  • Fatigue
  • Vomiting
  • Irritability
  • Insomnia
  • Diarrhea
  • Anxiety
  • Seizures
  • Hyperhidrosis (excessive sweating)

In addition, the following symptoms are noted as relating to other antidepressants:

dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesias such as electric shock sensations), anxiety, confusion, headache, lethargy, emotional lability, insomnia, hypomania, tinnitus, and seizures).

Individual reports from people who stop taking Cymbalta range from mild headaches to life debilitating conditions. There is a wide range of possible Cymbalta withdrawal symptoms and the severity and duration of those symptoms depend on numerous factors. Here are some anecdotal reports of Cymbalta withdrawal symptoms:

  • I’m finally completely off Cymbalta. I can’t believe I actually made it through the horrible withdrawal symptoms. It took eight horrible weeks…The worst part for me was what I call brain zapping. It felt like electrical currents going through my brain every time I moved my head. I thought I was going crazy…I’m having a major problem with my anger towards Eli Lily. I even e-mailed the FDA about how awful the withdrawal was. Why don’t the doctors warn us about this? I still have a problem with depression, but I’m scared to try another med…
  • I have been weaning myself off Cymbalta for the last 3 weeks and it has been hell!! Not only have I had crazy mood swings I have been having muscle spasms around my face… I was on 30mg, and started opening the caps and taking half, well I have been out for 3days and feel very uncomfortable. How can doctors prescribe meds without seriously thinking of the side effects? Cymbalta only made me more of a mess, I had mood swings daily. To anyone planning on taking this med please read all about it!!!!
  • I wonder why Cymbalta did not have more extensive “testing” before prescribed to us. I was slowly weaned under Doctor’s care but stilled became extremely ill. I suffered “seizures” on top of everything else. I’m still on my road to recovery (4 weeks completely off Cymbalta). I’m still weak and suffer withdrawals or the effects of seizures but I’m under a good Neurologist care.

PowerPoint, Cymbalta (Duloxetine) Discontinuation Syndrome:
Issues of Scope, Severity, Duration & Management
presented to the United States Food and Drug Administration on June 9, 2009.

Before stopping any medication you must first consult with your healtcare provider.