An estimated 5,300 people were killed in the United States in 2005 by large trucks. Accidents involving trucks are among the most dangerous and most deadly in the nation. The states with the highest truck crash fatality rates are Texas, California, Florida and Georgia.

• 442,000 large trucks were involved in traffic crashes in 2005.
• 4,932 large trucks were involved in fatal crashes in 2005.
• 5,212 people died from large truck accidents, 12% of all the traffic fatalities reported in 2005.
• 114,000 people were injured in large truck accidents in 2005.
• One out of eight traffic fatalities in 2005 resulted from a collision involving a large truck.
• About 2/3 of fatal truck accidents occur in rural areas.
• Almost 2/3 of fatal truck accidents occur in daylight.
• 81.2% occur on dry roads.
• 84.6% occur in "normal" (i.e. no precipitation) weather conditions.
• Tractors pulling one semi trailer are the most common truck configuration, accounting for about 60% of all trucks involved in a fatal accident.
• Texas, California, and Florida had the greatest number of truck involvements on average.
• An average of 366 pedestrians and 69 bicyclists are killed each year in traffic accidents involving trucks.
• 29.7% of fatal truck accidents, occur on state highways, 24.5% on U.S. highways, and 25.8% on Interstate highways.

• In 9.2% of fatal truck accidents, the other vehicle crossed the center line of the road and struck the truck head on.